Genetic analysis of cholesterol gallstone formation: Searching for Lith (gallstone) genes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11894-004-0042-1.pdf
Reference87 articles.
1. Korstanje R, Paigen B: From QTL to gene: the harvest begins. Nat Genet 2002, 31:235–236.
2. Lammert F, Carey MC, Paigen B: Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map. Gastroenterology 2001, 120:221–238.
3. Admirand WH, Small DM: The physicochemical basis of cholesterol gallstone formation in man. J Clin Invest 1968, 47:1043–1052.
4. Carey MC, Small DM: The physical chemistry of cholesterol solubility in bile: relationship to gallstone formation and dissolution in man. J Clin Invest 1978, 61:998–1026.
5. Wang DQ-H, Paigen B, Carey MC: Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: physical-chemistry of gallbladder bile. J Lipid Res 1997, 38:1395–1411. These authors investigated the physical-chemical phenotypes of mouse gallbladder biles in the gallstone-susceptible C57L/J strain compared with the gallstone-resistant AKR/J strain and their F1 progeny during 56 days on the lithogenic diet. The definition of the physical chemistry of lithogenesis should aid in further elucidation of the Lith genes and the proteins they encode.
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