The recent advances in the mathematical modelling of human pluripotent stem cells-Reference-Cited by-同舟云学术

The recent advances in the mathematical modelling of human pluripotent stem cells

Published:2020-01-27 Issue:2 Volume:2 Page:
ISSN:2523-3963
Container-title:SN Applied Sciences
language:en
Short-container-title:SN Appl. Sci.

Author:

Wadkin L. E.^ORCID,Orozco-Fuentes S.,Neganova I.,Lako M.,Shukurov A.,Parker N. G.

Abstract

AbstractHuman pluripotent stem cells hold great promise for developments in regenerative medicine and drug design. The mathematical modelling of stem cells and their properties is necessary to understand and quantify key behaviours and develop non-invasive prognostic modelling tools to assist in the optimisation of laboratory experiments. Here, the recent advances in the mathematical modelling of hPSCs are discussed, including cell kinematics, cell proliferation and colony formation, and pluripotency and differentiation.

Funder

Innovative Medicines Initiative

European Research Council

National Centre for the Replacement, Refinement and Reduction of Animals in Research

Biotechnology and Biological Sciences Research Council

Russian Government Program

Consejo Nacional de Ciencia y Tecnología

Leverhulme Trust

Publisher

Springer Science and Business Media LLC

Subject

General Earth and Planetary Sciences,General Physics and Astronomy,General Engineering,General Environmental Science,General Materials Science,General Chemical Engineering

Link

http://link.springer.com/content/pdf/10.1007/s42452-020-2070-3.pdf

Reference112 articles.

1. Ebert AD, Svendsen CN (2010) Human stem cells and drug screening: opportunities and challenges. Nat Rev Drug Discov 9(5):367–372

2. Zhu Z, Huangfu D (2013) Human pluripotent stem cells: an emerging model in developmental biology. Development 140(4):705–717

3. Liu YW, Chen B, Yang X, Fugate JA, Kalucki FA, Futakuchi-Tsuchida A, Couture L, Vogel KW, Astley CA, Baldessari A, Ogle J, Don CW, Steinberg ZL, Seslar SP, Tuck SA, Tsuchida H, Naumova AV, Dupras SK, Lyu MS, Lee J, Hailey DW, Reinecke H, Pabon L, Fryer BH, MacLellan WR, Thies RS, Murry CE (2018) Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates. Nat Biotechnol 36(7):597–605

4. Jacobson EF, Tzanakakis ES (2017) Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: innovations, challenges and future directions. J Biol Eng 11:21

5. Hallam D, Hilgen G, Dorgau B, Zhu L, Yu M, Bojic S, Hewitt P, Schmitt M, Uteng M, Kustermann S, Steel D, Nicholds M, Thomas R, Treumann A, Porter A, Sernagor E, Armstrong L, Lako M (2018) Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency. Stem Cells 36(10):1535–1551

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