Subtype-selective blockade of cardiac muscarinic receptors inhibits vagal chronotropic responses in cats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Physiology (medical),Clinical Biochemistry,Physiology
Link
http://link.springer.com/content/pdf/10.1007/s00424-007-0347-7.pdf
Reference45 articles.
1. Akahane K, Furukawa Y, Karasawa Y, Chiba S (1990) Muscarinic receptor subtypes mediating negative chrono- and inotropic responses in isolated, blood-perfused dog right atria. J Auton Pharmacol 10:39–48
2. Barlow RB, Berry KJ, Glenton PAM, Nikolaou NM, Soh KS (1976) A comparison of affinity constants for muscarine-sensitive acetylcholine receptors in guinea-pig atrial pacemaker cells at 29°. C and in ileum at 29°. C and 37°. C. Br J Pharmacol 58:613–620
3. Bloom JW, Yamamura HI, Baumgartener C, Halonen M (1987) A muscarinic receptor with high affinity for pirenzepine mediates vagally induced bronchoconstriction. Eur J Pharmacol 133:21–27
4. Boyett MR, Kodama I, Honjo H, Arai A, Suzuki R, Toyama J (1995) Ionic basis of the chronotropic effect of acetylcholine on the rabbit sinoatrial node. Cardiovasc Res 29:867–878
5. Brehm G, Lindmar R, Loffelholz K (1992) Inhibitory and excitatory muscarinic receptors modulating the release of acetylcholine from the postganglionic parasympathetic neuron of the chicken heart. Naunyn-Schmiedeberg’s Arch Pharmacol 346:375–382
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1. Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation;Cardiovascular Research;2009-05-20
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