Ginkgolide B caused the activation of the Akt/eNOS pathway through the antioxidant effect of SOD1 in the diabetic aorta
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Physiology (medical),Clinical Biochemistry,Physiology
Link
https://link.springer.com/content/pdf/10.1007/s00424-023-02790-3.pdf
Reference43 articles.
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2. Anwar MA, Samaha AA, Ballan S, Saleh AI, Iratni R, Eid AH (2017) Salvia fruticosa induces vasorelaxation in rat isolated thoracic aorta: role of the PI3K/Akt/eNOS/NO/cGMP signaling pathway. Sci Rep 7:686. https://doi.org/10.1038/s41598-017-00790-9
3. Avogaro A, Albiero M, Menegazzo L, de Kreutzenberg S, Fadini GP (2011) Endothelial dysfunction in diabetes: the role of reparatory mechanisms. Diabetes Care 34:S285–S290. https://doi.org/10.2337/dc11-s239
4. Azul L, Leandro A, Boroumand P, Klip A, Seiça R, Sena CM (2020) Increased inflammation, oxidative stress and a reduction in antioxidant defense enzymes in perivascular adipose tissue contribute to vascular dysfunction in type 2 diabetes. Free Radic Biol Med 146:264–274. https://doi.org/10.1016/j.freeradbiomed.2019.11.002.
5. Chen X, Salwinski S, Lee TJ (1997) Extracts of Ginkgo biloba and ginsenosides exert cerebral vasorelaxation via a nitric oxide pathway. Clin Exp Pharmacol Physiol 24:958–959. https://doi.org/10.1111/j.1440-1681.1997.tb02727.x
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