Altered force generation and cell-to-cell contractile imbalance in hypertrophic cardiomyopathy

Author:

Kraft Theresia,Montag JudithORCID

Funder

Deutsche Forschungsgemeinschaft

Medizinischen Hochschule Hannover

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Clinical Biochemistry,Physiology

Reference137 articles.

1. Alamo L, Ware JS, Pinto A, Gillilan RE, Seidman JG, Seidman CE, Padron R (2017) Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes. Elife 6. https://doi.org/10.7554/eLife.24634

2. Aldag-Niebling D, Radocaj A, Hilfigker-Kleiner D, Dos Remedios C, Brenner B, Kraft T (2018) Hypertrophic cardiomyopathy: variable expression of myosin-binding protein C from cell-to-cell and functional imbalance among individual cardiomyocytes. Biophys J 114:312A

3. Al-Khayat HA, Kensler RW, Squire JM, Marston SB, Morris EP (2013) Atomic model of the human cardiac muscle myosin filament. Proc Natl Acad Sci U S A 110:318–323. https://doi.org/10.1073/pnas.1212708110

4. Amin AS, Giudicessi JR, Tijsen AJ, Spanjaart AM, Reckman YJ, Klemens CA, Tanck MW, Kapplinger JD, Hofman N, Sinner MF, Muller M, Wijnen WJ, Tan HL, Bezzina CR, Creemers EE, Wilde AA, Ackerman MJ, Pinto YM (2012) Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner. Eur Heart J 33:714–723. https://doi.org/10.1093/eurheartj/ehr473

5. Anderson RL, Trivedi DV, Sarkar SS, Henze M, Ma W, Gong H, Rogers CS, Gorham JM, Wong FL, Morck MM, Seidman JG, Ruppel KM, Irving TC, Cooke R, Green EM, Spudich JA (2018) Deciphering the super relaxed state of human beta-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers. Proc Natl Acad Sci U S A 115:E8143–E8152. https://doi.org/10.1073/pnas.1809540115

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