Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress

Author:

Matsunaga Toshiyuki,Tsuji Yoshitaka,Kaai Kairyu,Kohno Saki,Hirayama Renzo,Alpers David H.,Komoda Tsugikazu,Hara Akira

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference36 articles.

1. Rudi J, Werle S, Bergtholdt D et al (2005) Infusional 5-fluorouracil and mitomycin C: an effective regimen in the treatment of advanced gastric cancer. Onkologie 28:128–132

2. Hartmann JT, Pintoffl JP, Al-Batran SE et al (2007) Mitomycin C plus infusional 5-fluorouracil in platinum-refractory gastric adenocarcinoma: an extended multicenter phase II study. Onkologie 30:235–240

3. Kretzschmar A, Reichardt P, Thuss-Patience PC et al (2000) Weekly 24 hour infusion of high-dose 5-fluorouracil plus folinic acid in combination with mitomycin C for the treatment of advanced gastric cancer. Oncology 59:14–17

4. Hofheinz R, HartungG SamelS et al (2002) High-dose 5-fluorouracil/folinic acid in combination with three-weekly mitomycin C in the treatment of advanced gastric cancer. A phase-II study. Onkologie 25:255–260

5. Ren Q, Van Groeningen CJ, Hardcastle A et al (1997) Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells. Oncol Res 9:77–88

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