Assessing the translational value of pre-clinical studies for clinical response rate in oncology: an exploratory investigation of 42 FDA-approved small-molecule targeted anticancer drugs-Reference-Cited by-同舟云学术

Assessing the translational value of pre-clinical studies for clinical response rate in oncology: an exploratory investigation of 42 FDA-approved small-molecule targeted anticancer drugs

Published:2020-05-18 Issue:6 Volume:85 Page:1015-1027
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Liu Wenying Angela,Yu Li,Morcos Peter N.,Mercier Francois,Brennan Barbara J.^ORCID

Funder

F. Hoffmann-La Roche

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s00280-020-04076-2.pdf

Reference110 articles.

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3. Sacks LV, Shamsuddin HH, Yasinskaya YI et al (2014) Scientific and regulatory reasons for delay and denial of FDA approval of initial applications for new drugs, 2000–2012. JAMA 311:378–384. https://doi.org/10.1001/jama.2013.282542

4. Mathijssen RHJ, Sparreboom A, Verweij J (2014) Determining the optimal dose in the development of anticancer agents. Nat Rev Clin Oncol 11:272–281. https://doi.org/10.1038/nrclinonc.2014.40

5. Sachs JR, Mayawala K, Gadamsetty S et al (2016) Optimal Dosing for Targeted Therapies in Oncology: Drug Development Cases Leading by Example. Clin Cancer Res Off J Am Assoc Cancer Res 22:1318–1324. https://doi.org/10.1158/1078-0432.CCR-15-1295

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