In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative

Author:

Hollingshead Melinda,Alley Michael,Burger Angelika M.,Borgel Suzanne,Pacula-Cox Christine,Fiebig Heinz-Herbert,Sausville Edward A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference34 articles.

1. Alley MC, Scudiero DA, Monks A, Hursey ML, Czerwinski MJ, Fine DL, Shoemaker RH, Mayo JG, Boyd MR (1988) Feasibility of drug screening with panels of human tumor lines using a microculture tetrazolium assay. Cancer Res 48:589–601

2. Alley MC, Pacula-Cox CM, Hollingshead, MG, Camalier RF, Mayo JG, Plowman, J, Malspeis L (1995) Utility of a PVDF filter plate assay to facilitate selection of tumor cell lines for in vivo drug testing. Proc Am Assoc Cancer Res 36:305

3. Banerji U, Clarke P, Walton M, O‘Donnell A, Raynaud F, Turner A, Judson I, Workman P (2003) Preclinical and clinical activity of the molecular chaperone inhibitor 17-allylamino-17-demethoxygeldanamycin (17AAG) in malignant melanoma (2nd edn) (abstract 2966). Proc Am Assoc Cancer Res 44:587

4. Beliakoff J, Bagatell R, Paine-Murrieta G, Taylor CW, Lykkesfeldt AE, Whitesell L (2003) Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors. Clin Cancer Res 9:4961–4971

5. Bonvini P, Gastaldi T, Falini B, Rosolen A (2002) Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin. Cancer Res 62:1559–1566

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