Pharmacokinetics and Oral Bioavailability of Coumarins and Carbazole Alkaloids from Clausena harmandiana Root Bark in Rats

Author:

Mekjaruskul CatheleeyaORCID,Sungthong BunleuORCID,Puthongking PloenthipORCID,Boonyarat ChantanaORCID

Funder

Thailand Science Research and Innovation

Publisher

Springer Science and Business Media LLC

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference26 articles.

1. Chaichantipyuth C, Pummangura S, Naowsaran K, Thanyavuthi D, Anderson JE, McLaughlin JL (1988) Two new bioactive carbazole alkaloids from the root bark of Clausena harmandiana. J Nat Prod 51:1285–1288. https://doi.org/10.1021/np50060a044

2. Chatchawanchonteera A, Keeratikulapas P, Mungmai N, Chitsanoor S, Boottasri A, Kaenchumpa P, Wangboonsakul J (2009) Antimicrobial activity of Clausena harmandiana extract against bacteria isolated from dogs with otitis externa. KKU Vet J 19:48–55

3. Daodee S, Wangboonskul J, Yenjai C, Boonyarat C, Monthakantirat O (2012) Determination of five carbazole alkaloids from the root of Clausena harmandiana by high performance liquid chromatography. Isan J Pharm Sci 8:94–100

4. Davies B, Morris T (1993) Physiological parameters in laboratory animals and humans. Pharm Res 10:1093–1095. https://doi.org/10.1023/A:1018943613122

5. Feng C, Ruan JL, Cai YL (2010a) Simultaneous determination and pharmacokinetics of four coumarins in rat plasma after oral administration of traditional Chinese medicine “YIGONG” capsule by SPE-HPLC. J Braz Chem Soc 21:2272–2277. https://doi.org/10.1590/S0103-50532010001200014

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