Investigation of the Anti-asthmatic Activity of Solidagenone, In Vitro Toxicity Versus In Silico Studies
Author:
Funder
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
Publisher
Springer Science and Business Media LLC
Subject
General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s43450-023-00479-3.pdf
Reference23 articles.
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2. Bortoleti BTS, Gonçalves MD, Tomiotto-Pellissier F, Contato VM, Silva TF, de Matos RLN, Detoni MB, Rodrigues ACJ, Carloto AC, Lazarin DB, Arakawa NS, Costa IN, Conchon-Costa I, Miranda-Sapla MM, Wowk PF, Pavanelli WR (2021) Solidagenone acts on promastigotes of L. amazonensis by inducing apoptosis-like processes on intracellular amastigotes by IL-12p70/ROS/NO pathway activation. Phytomedicine 85:153536. https://doi.org/10.1016/j.phymed.2021.153536
3. Cuadrado I, Amesty Á, Cedrón JC, Oberti JC, Estévez-Braun A, Hortelano S, de las Heras B (2018) Semisynthesis and inhibitory effects of solidagenone derivatives on TLR-mediated inflammatory responses. Molecules 23:3197. https://doi.org/10.3390/molecules23123197
4. De Brito TM, Amendoeira FC, de Oliveira TB, Frutuoso VS, Ferraris FK, Valverde SS (2020) Extract of Solidago chilensis Meyen inflorescences: cytotoxicity and inhibitory activity on nitric oxide synthesis in activated macrophage cell line J774A.1. Braz J Pharm Sci 56:e17707. https://doi.org/10.1590/s2175-97902020000117707
5. El-Saadi MW, Williams-Hart T, Salvatore BA, Mahdavian E (2015) Use of in-silico assays to characterize the ADMET profile and identify potential therapeutic targets of fusarochromanone, a novel anti-cancer agent. In Silico Pharmacol 3:6. https://doi.org/10.1186/s40203-015-0010-5
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