Epiisopiloturine from Pilocarpus microphyllus Leaves Reduces Intestinal Mucositis Through Cyclooxygenase-2 Pathway

Author:

Barbosa Maria Lucianny LimaORCID,Campelo Matheus da SilvaORCID,Pimenta Helder BindáORCID,Rebouças Conceição da Silva MartinsORCID,de Miranda João Antônio LealORCID,Brito Gerly Anne de CastroORCID,Leitão Renata Ferreira de CarvalhoORCID,Vale Larice de CarvalhoORCID,Veras Leiz Maria CostaORCID,Medeiros Jand Venes RolimORCID,Ribeiro Maria Elenir Nobre PinhoORCID,Cerqueira Gilberto SantosORCID

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Springer Science and Business Media LLC

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference31 articles.

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2. Al-Rashdi AS, Salama SM, Alkiyumi SS, Abdulla MA, Hadi AHA, Abdelwahab SI, Taha MM, Hussiani J, Asykin N (2012) Mechanisms of gastroprotective effects of ethanolic leaf extract of Jasminum sambac against HCl/ethanol-induced gastric mucosal injury in rats. Evid Based Complement Altern Med 2012:786426. https://doi.org/10.1155/2012/786426

3. Araújo CV, Lazzarotto CR, Aquino CC, Figueiredo IL, Costa TB, de Oliveira ALA, Ribeiro RA, Bertolini LR, Lima AAM, Brito G, Oriá RB (2015) Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient mice. Braz J Med Biol Res 48:493–501. https://doi.org/10.1590/1414-431X20144360

4. Bastos RW, Pedroso SHSP, Vieira AT, Moreira LMC, França CS, Cartelle CT, Arantes RME, Generoso SV, Cardoso VN, Neves MJ, Nicoli JR, Martins FS (2016) Saccharomyces cerevisiae UFMG A-905 treatment reduces intestinal damage in a murine model of irinotecan-induced mucositis. Benef Microbes 7:549–557. https://doi.org/10.3920/BM2015.0190

5. Carneiro-Filho BA, Lima IPF, Araujo DH, Cavalcante MC, Carvalho GHP, Brito GA, Lima V, Monteiro SMN, Santos FN, Ribeiro RA, Lima AAM (2004) Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis. Dig Dis Sci 49:65–72. https://doi.org/10.1023/b:ddas.0000011604.45531.2c

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