Abstract
Abstract
Purpose of Review
We explore how to develop Maastricht category I and II donation in the UK. We discuss lessons learned from previous UK pilots and define future steps in the journey to establishing a sustainable uDCD programme in the UK.
Recent Findings
The emergence of normothermic regional perfusion (NRP) as a successful strategy in cDCD donation with excellent clinical results creates the optimal platform for the development of a uDCD programme. Coordinated logistics with ambulance services and ED departments, embedded donor coordination in ED, public acceptance and wider discussion on acceptable peri-mortem interventions are key for future developments.
Summary
A uDCD programme in the UK is feasible. Despite an increase in public awareness and recent changes in legislation, there remain several challenges. Recent advances in perfusion and preservation and an established national retrieval infrastructure, create the premises for future sustainable developments.
Publisher
Springer Science and Business Media LLC
Subject
Transplantation,Nephrology,Hepatology,Immunology,Surgery
Reference24 articles.
1. NHS Blood and Transplant. Organ donation and transplantation 2030: meeting the need. A ten year vision for organ donation and transplantation in the United Kingdom.
2. NHS Blood and Transplant. Organ donation and transplantation activity report 2019/20. 2020.
3. Organización Nacional de Trasplantes and Council of Europe. Newsletter Transplant. International Figures on Donation and Transplantation 2019.
4. Barlow AD, Metcalfe MS, Johari Y, Elwell R, Veitch PS, Nicholson ML. Case-matched comparison of long-term results of non-heart beating and heart-beating donor renal transplants. Br J Surg. 2009;96(6):685–91. https://doi.org/10.1002/bjs.6607.
5. Balupuri S, Buckley P, Snowden C, Mustafa M, Sen B, Griffiths P, et al. The trouble with kidneys derived from the non heart-beating donor: a single center 10-year experience. Transplantation. 2000;69(5):842–6. https://doi.org/10.1097/00007890-200003150-00029.