Gastrointestinal Polyposis in Childhood: Clinicopathologic and Genetic Features-Reference-Cited by-同舟云学术

Gastrointestinal Polyposis in Childhood: Clinicopathologic and Genetic Features

Published:2003-09 Issue:5 Volume:6 Page:371-391
ISSN:1093-5266
Container-title:Pediatric and Developmental Pathology
language:en
Short-container-title:Pediatr Dev Pathol

Author:

Lowichik Amy¹²,Jackson W. Daniel³⁴,Coffin Cheryl M.¹²

Affiliation:

1. Department of Pathology, University of Utah Health Sciences Center, 30 N. 1900 E, Salt Lake City, UT 84132-2501, USA

2. Department of Pathology, Primary Children's Medical Center, 100 North Medical Drive, Salt Lake City, UT 84113-1100, USA

3. Department of Pediatrics, University of Utah School of Medicine, 30 N. 1900 E, Salt Lake City, UT 84132-2501, USA

4. Division of Pediatric Gastroenterology/Nutrition, Primary Children's Medical Center, 100 North Medical Drive, Salt Lake City, UT 84113-1100, USA

Abstract

Gastrointestinal polyps and certain extraintestinal lesions in children may herald a hereditary polyposis syndrome, with an increased risk of neoplasia and other health problems for both children and their relatives. The availability of molecular/genetic screening tests has increased early diagnosis of younger members of known polyposis families. This article reviews the gross and microscopic features of polyposis syndromes of childhood and summarizes the molecular/genetic advances in this field. Clinical management is also briefly discussed.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1007/s10024-002-0701-x

Reference160 articles.

1. Symptomatic Colonic Polyps in Childhood: Not So Benign

2. Clinical Management and Genetics of Gastrointestinal Polyps in Children

3. Gastrointestinal polyps in children: Advances in molecular genetics, diagnosis, and management

4. Protean PTEN: Form and Function

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