Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide

Author:

Patel Mallika P.,Woodring Sarah,Randazzo Dina M.,Friedman Henry S.,Desjardins Annick,Healy Patrick,Herndon James E.,McSherry Frances,Lipp Eric S.,Miller Elizabeth,Peters Katherine B.,Affronti Mary LouORCID

Funder

Merck

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference30 articles.

1. Abdel-Rahman O (2016) Neurokinin-1 inhibitors in the prevention of nausea and vomiting from highly emetogenic chemotherapy: a network meta-analysis. Ther Adv Med Oncol 8(5):396–406. https://doi.org/10.1177/1758834016654902

2. Aapro M (2018) Searching for perfection: further progress in management of chemotherapy-induced nausea and vomiting-concluding thoughts. Support Care Cancer 26(Suppl 1):35–37. https://doi.org/10.1007/s00520-018-4121-5

3. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352(10):987–996. https://doi.org/10.1056/NEJMoa043330

4. Affronti ML, Woodring S, Peters KB, Herndon JE 2nd, McSherry F, Healy PN, Desjardins A, Vredenburgh JJ, Friedman HS (2017) A phase II single-arm trial of palonosetron for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in malignant glioma patients receiving multidose irinotecan in combination with bevacizumab. Ther Clin Risk Manag 13:33–40. https://doi.org/10.2147/TCRM.S122480

5. Affronti ML, Schneider SM, Herndon JE 2nd, Schlundt S, Friedman HS (2014) Adherence to antiemetic guidelines in patients with malignant glioma: a quality improvement project to translate evidence into practice. Support Care Cancer 22(7):1897–1905. https://doi.org/10.1007/s00520-014-2136-0

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