Pharmacokinetic and pharmacodynamic aspects of concomitant mibefradil-digoxin therapy at therapeutic doses-Reference-Cited by-同舟云学术

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Pharmacokinetic and pharmacodynamic aspects of concomitant mibefradil-digoxin therapy at therapeutic doses

Published:1999-06 Issue:2 Volume:24 Page:133-140
ISSN:0378-7966
Container-title:European Journal of Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Eur. J. Drug Metab. Pharmacokinet.

Author:

Peters J.,Welker H. A.,Bullingham R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

http://link.springer.com/content/pdf/10.1007/BF03190358.pdf

Reference24 articles.

1. Mishra S., Hermsmeyer K. (1994): Selective inhibition of T-type Ca2+ channels by Ro 40−5967. Circ. Res., 75: 144–148.

2. Clozel J-P., Banken L., Osterrieder W. (1989): Effects of Ro 40–5 967, a novel calcium antagonist, on myocardial function during ischemia induced by lowering coronary perfusion pressure in dogs. comparison with verapamil. J. Cardiovasc. Pharmacol., 14: 713–721.

3. Clozel J-P., Véniant M., Osterrieder W. (1990): The structurally novel Ca2+ channel blocker Ro 40–5967, which binds to the [3H]-desmethoxyverapamil receptor, is devoid of the negative inotropic effects of verapamil in normal and failing rat hearts. Cardiovasc. Drugs Ther., 4: 731–736.

4. Schmitt R., Kleinbloesem, C., Belz, G.et al. (1992): Hemodynamic and humoral effects of the novel calcium antagonist Ro 40–5967 in patients with hypertension. Clin. Pharmacol. Ther., 52: 314–323.

5. Bernink P., Prager G., Schelling A., Kobrin I. (1996): Antihypertensive properties of the novel calcium antagonist mibefradil (Ro 40–5967): a new generation of calcium antagonists? Hypertension, 27: 426–432.

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