Enriching CBT by Neuroscience: Novel Avenues to Achieve Personalized Treatments
-
Published:2020-10-15
Issue:1
Volume:14
Page:182-195
-
ISSN:1937-1217
-
Container-title:International Journal of Cognitive Therapy
-
language:en
-
Short-container-title:J Cogn Ther
Author:
Månsson Kristoffer N TORCID, Lueken Ulrike, Frick Andreas
Abstract
AbstractAlthough cognitive behavioral therapy (CBT) is an established and efficient treatment for a variety of common mental disorders, a considerable number of patients do not respond to treatment or relapse after successful CBT. Recent findings and approaches from neuroscience could pave the way for clinical developments to enhance the outcome of CBT. Herein, we will present how neuroscience can offer novel perspectives to better understand (a) the biological underpinnings of CBT, (b) how we can enrich CBT with neuroscience-informed techniques (augmentation of CBT), and (c) why some patients may respond better to CBT than others (predictors of therapy outcomes), thus paving the way for more personalized and effective treatments. We will introduce some key topics and describe a selection of findings from CBT-related research using tools from neuroscience, with the hope that this will provide clinicians and clinical researchers with a brief and comprehensible overview of the field.
Funder
Vetenskapsrådet Deutsche Forschungsgemeinschaft Kjell och Märta Beijers Stiftelse Riksbankens Jubileumsfond Hjärnfonden
Publisher
Springer Science and Business Media LLC
Subject
Experimental and Cognitive Psychology
Reference67 articles.
1. Ågren, T., Engman, J., Frick, A., Björkstrand, J., Larsson, E.-M., Furmark, T., & Fredrikson, M. (2012). Disruption of reconsolidation erases a fear memory trace in the human amygdala. Science, 337(6101), 1550–1552. 2. Andersson, E., Crowley, J. J., Lindefors, N., Ljótsson, B., Hedman-Lagerlöf, E., Boberg, J., El Alaoui, S., Karlsson, R., Lu, Y., Mattheisen, M., Kähler, A. K., Svanborg, C., Mataix-Cols, D., Mattsson, S., Forsell, E., Kaldo, V., Schalling, M., Lavebratt, C., Sullivan, P. F., & Rück, C. (2018). Genetics of response to cognitive behavior therapy in adults with major depression: A preliminary report. Molecular Psychiatry, 24, 484–490. https://doi.org/10.1038/s41380-018-0289-9. 3. Andersson, E., Hedman, E., Enander, J., Radu Djurfeldt, D., Ljótsson, B., Cervenka, S., Isung, J., Svanborg, C., Mataix-Cols, D., Kaldo, V., Andersson, G., Lindefors, N., & Rück, C. (2015). D-Cycloserine vs placebo as adjunct to cognitive behavioral therapy for obsessive-compulsive disorder and interaction with antidepressants: A randomized clinical trial. JAMA Psychiatry, 72(7), 659–667. 4. Baxter Jr., L. R., Schwartz, J. M., Bergman, K. S., Szuba, M. P., Guze, B. H., Mazziotta, J. C., Alazraki, A., Selin, C. E., Ferng, H. K., & Munford, P. (1992). Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Archives of General Psychiatry, 49(9), 681–689. 5. Björkstrand, J., Agren, T., Åhs, F., Frick, A., Larsson, E.-M., Hjorth, O., Furmark, T., & Fredrikson, M. (2016). Disrupting reconsolidation attenuates long-term fear memory in the human amygdala and facilitates approach behavior. Current Biology, 26(19), 2690–2695.
Cited by
15 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|