Mechanism of irreversible inactivation of phenylalanine-4- and tryptophan-5-hydroxylases by [4-36Cl, 2-14C]p-chlorophenylalanine: A revision-Reference-Cited by-同舟云学术

Mechanism of irreversible inactivation of phenylalanine-4- and tryptophan-5-hydroxylases by [4-36Cl, 2-14C]p-chlorophenylalanine: A revision

Published:1982-01 Issue:1 Volume:7 Page:13-26
ISSN:0364-3190
Container-title:Neurochemical Research
language:en
Short-container-title:Neurochem Res

Author:

G�l E. M.,Whitacre D. H.

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,General Medicine,Biochemistry

Link

http://link.springer.com/content/pdf/10.1007/BF00965065.pdf

Reference31 articles.

1. Koe, B. K., andWeissman, A. 1966.P-Chlorophenylalanine: Specific depletor of brain serotonin. J. Pharmacol. Exper. Ther. 154:499?516.

2. Jequier, E., Lovenberg, W., andSjoerdsma, A. 1967. Tryptophan hydroxylase inhibition. The mechanism by whichp-chlorophenylalanine depletes rat brain serotonin. Molecular Pharmacol. 3:274?278.

3. Gál, E. M., Roggeveen, A. E., andMillard, S. A. 1970. DL-2-14CP-chlorophenylalanine as an inhibitor of tryptophan-5-hydroxylase. J. Neurochem. 17:1221?1235.

4. Gál, E. M., andMillard, S. A. 1971. The mechanism of inhibition of hydroxylases in vivo byp-chlorophenylalanine: The effect of cycloheximide. Biochem. Biophys. Acta. 227:32?41.

5. Kaufman, S. 1962. Phenylalanine hydroxylase. Pages 809?814in J. P. Colowick, andN. O. Kaplan (eds.), Methods of Enzymology, Vol. V, Academic Press, New York.

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