Hydroxysteroid sulfotransferase and a specific UDP-glucuronosyltransferase are involved in the metabolism of digitoxin in man
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00165306.pdf
Reference31 articles.
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2. Campbell NR, Van Loon JA, Weinshilboum RM (1987) Human liver phenol sulfotransferase: Assay conditions, biochemical properties and partial purification of isoenzymes of the thermostable form. Biochem Pharmacol 36:1435?1446
3. Castle MC (1980) Glucuronidation of digitalis glycosides by rat liver microsomes. Stimulation by spironolactone and pregnenolone 16?-carbonitrile. Biochem Pharmacol 29:1497?1502
4. Castle MC, Lage GL (1974) Cleavage by ?-glucuronidase of the water-soluble metabolites of digitoxin excreted in the bile of control and spironolactone-pretreated rats. Toxicol Appl Pharmacol 27:641?647
5. Falany CN, Vazquez ME, Kalb JM (1989) Purification and characterization of human liver dehydroepiandrosterone sulphotransferase. Biochem J 260:641?646
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1. Effect of spironolactone on the expression of rat hepatic UDP-glucuronosyltransferase;Biochemical Pharmacology;2003-07
2. Convergence of Three Methods to Resolve Discrepant Immunoassay Digitoxin Results;Clinical Chemistry;1997-09-01
3. Human dehydroepiandrosterone sulfotransferase: molecular cloning of cDNA and genomic DNA;Chemico-Biological Interactions;1994-06
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5. Sulfotransferase Enzymes;Handbook of Experimental Pharmacology;1994
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