Roles of CYP2C9 and its variants (CYP2C9*2 and CYP2C9*3) in the metabolism of 6-methoxy-2-napthylacetic acid, an active metabolite of the prodrug nabumetone-Reference-Cited by-同舟云学术

Roles of CYP2C9 and its variants (CYP2C9*2 and CYP2C9*3) in the metabolism of 6-methoxy-2-napthylacetic acid, an active metabolite of the prodrug nabumetone

Published:2019-01-29 Issue:1 Volume:50 Page:71-79
ISSN:2093-5552
Container-title:Journal of Pharmaceutical Investigation
language:en
Short-container-title:J. Pharm. Investig.

Author:

Matsumoto Kaori,Hasegawa Tetsuya,Ohara Kosuke,Takei Chihiro,Akimoto Masayuki

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science

Link

http://link.springer.com/article/10.1007/s40005-019-00428-0/fulltext.html

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3. Dennis VC, Thomas BK, Hanlon JE (2000) Potentiation of oral anticoagulation and hemarthrosis associated with nabumetone. Pharmacotherapy 20:234–239

4. Hanatani T, Fukuda T, Onishi S, Funae Y, Azuma J (2003) No major difference in inhibitory susceptibility between CYP2C9.1 and CYP2C9.3. Eur J Clin Pharmacol 59:233–235

5. Iida I, Miyata A, Arai M, Hirota M, Akimoto M, Higuchi S, Kobayashi K, Chiba K (2004) Catalytic roles of CYP2C9 and its variants (CYP2C9*2 and CYP2C9*3) in lornoxicam 5′-hydroxylation. Drug Metab Dispos 32:7–9

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