Macrophages in Systemic Sclerosis: Novel Insights and Therapeutic Implications-Reference-Cited by-同舟云学术

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Macrophages in Systemic Sclerosis: Novel Insights and Therapeutic Implications

Published:2019-05-23 Issue:7 Volume:21 Page:
ISSN:1523-3774
Container-title:Current Rheumatology Reports
language:en
Short-container-title:Curr Rheumatol Rep

Author:

Toledo Diana M.,Pioli Patricia A.

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Scleroderma Foundation

National Institutes of Health p50 Specialized Center Grant, Research Diversity Supplement

John H. Copenhaver, Jr. and William H. Thomas, MD 1952 Junior Fellowship from Dartmouth Graduate Studies

Publisher

Springer Science and Business Media LLC

Subject

Rheumatology

Link

http://link.springer.com/content/pdf/10.1007/s11926-019-0831-z.pdf

Reference69 articles.

1. Assassi S, Swindell WR, Wu M, Tan FD, Khanna D, Furst DE, et al. Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis. Arthritis Rheum. 2015;67:3016–26.

2. Mahoney JM, Taroni J, Martyanov V, Wood TA, Greene CS, Pioli PA, et al. Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms. PLoS Comput Biol. 2015;11:e1004005.

3. • Taroni JN, Greene CS, Martyanov V, Wood TA, Christmann RB, Farber HW, et al. A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis. Genome Med. 2017;9:27 A meta-analysis combining multiple gene expression datasets from different SSc-affected tissues, identifying a cluster of genes associated with alternatively activated macrophages.

4. •• Hinchcliff M, Toledo DM, Taroni JN, Wood TA, Franks JM, Ball MS, et al. Mycophenolate mofetil treatment of systemic sclerosis reduces myeloid cell numbers and attenuates the inflammatory gene signature in skin. J Invest Dermatol. 2018;138:1301–10 This study focuses on the molecular effects of long-term MMF therapy on the macrophages in SSc patient skin.

5. Milano A, Pendergrass SA, Sargent JL, George LK, McCalmont TH, Connolly MK, et al. Molecular subsets in the gene expression signatures of scleroderma skin. PLoS One. 2008;3:e2696.

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