Connective tissue growth factor: A new and important player in the pathogenesis of fibrosis-Reference-Cited by-同舟云学术

Connective tissue growth factor: A new and important player in the pathogenesis of fibrosis

Published:2002-03 Issue:2 Volume:4 Page:136-142
ISSN:1523-3774
Container-title:Current Rheumatology Reports
language:en
Short-container-title:Curr Rheumatol Rep

Author:

Leask Andrew,Holmes Alan,Abraham David J.

Publisher

Springer Science and Business Media LLC

Subject

Rheumatology

Link

http://link.springer.com/content/pdf/10.1007/s11926-002-0009-x.pdf

Reference71 articles.

1. Bradham DM, Igarashi A, Potter RL, Grotendorst GR: Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRCinduced immediate early gene product CEF-10. J Cell Biol 1991, 114:1285–1294. This paper describes the cloning and characterization of connective tissue growth factor (CTGF) from HUVECs and shows that CTGF is a member of the immediate early gene family. They demonstrate that CTGF has chemotactic and mitogenic effects toward fibroblast.

2. Ivkovic S, Gerth N, Segarini PR, Lyons KM: Connective tissue growth factor (CTGF) is essential for skeletal development in the mouse. Mol Pathol 2001, 54:118.

3. Lau LF, Lam SC: The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 1999, 248:44–57.

4. Igarashi A, Okochi H, Bradham DM, Grotendorst GR: Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 1993, 4:637–645.

5. Surveyor GA, Brigstock DR: Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation. Growth Factors 1999, 17:115–124. This paper demonstrated that CTGF is produced in several specific tissues and organs in a temporal- and spatial-specific manner during embryonic development; thus supporting the role of CTGF in reproduction, differentiation, and cell fate in prenatal life.

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