Glycoprotein receptor inhibitors in the management of acute coronary syndromes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11886-002-0066-9.pdf
Reference82 articles.
1. Heart and Stroke Facts: 1996 Statistical Supplement. Dallas: American Heart Association; 1996.
2. Topol EJ, Califf R, Granger C, et al.: A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 1996, 335:775–782.
3. PARAGON Investigators: International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina. Circulation 1998, 97:2386–2395.
4. Boersma E, Harrington RA, Moliterno DJ, et al.: Platelet glycoprotein IIb-IIIa Inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials. Lancet 2002, 359:189–198. This is an exceptional systematic review of large randomized trials highlighting the role of GP IIb/IIIa inhibitors in reducing cardiac complications in patients with ACS who were not routinely scheduled to undergo early coronary revascularization. This review observed a differential treatment effect of GP IIb/IIIa inhibitors between men and women with ACS which agrees with an observation from the PURSUIT trial of sex difference marking presence of significant CAD.
5. Lefkovits J, Plow EF, Topol EJ: Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine. N Engl J Med 1995, 332:1553–1559.
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