Physicochemical Characterization and In Vitro Digestibility Study of an In Silico Designed Recombinant Protein Enriched with Large Neutral Amino Acids and Lacking Phenylalanine for Phenylketonuria
Author:
Funder
CSIR-Central Food Technological Research Institute
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Biochemistry,Bioengineering,Analytical Chemistry
Link
https://link.springer.com/content/pdf/10.1007/s10930-021-10039-0.pdf
Reference60 articles.
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2. Rama Devi AR, Naushad SM (2004) Newborn screening in India. Ind J Pediatr 71:157–160
3. Soltanizadeh N, Mirmoghtadaie L (2014) Strategies used in production of phenylalanine-free foods for PKU management. Compr Rev Food Sci Food Saf 13:287–299
4. van Vliet D, Bruinenberg VM, Mazzola PN, van Faassen MHJR, de Blaauw P, Kema IP, Fokkema MRH, van Anholt RD, van der Zee EA, van Spronsen FJ (2015) Large neutral amino acid supplementation exerts its effect through three synergistic mechanisms: proof of principle in phenylketonuria mice. PLoS ONE 10(12):1–18. https://doi.org/10.1371/journal.pone.0143833
5. van Vliet D, Bruinenberg VM, Mazzola PN, van Faassen MHJR, de Blaauw P, Kema IP, Fokkema MRH, van Anholt RD, van der Zee EA, van Spronsen FJ (2018) Large neutral amino acids supplementation as an alternative to the phenylalanine-restricted diet in adults with phenylketonuria: evidence from adult Pah-enu2 mice. J Nutr Biochem 53:20–27
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