A Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Avagacestat (BMS-708163) in Healthy Young and Elderly Subjects-Reference-Cited by-同舟云学术

A Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Avagacestat (BMS-708163) in Healthy Young and Elderly Subjects

Published:2012-08-22 Issue:10 Volume:51 Page:681-693
ISSN:0312-5963
Container-title:Clinical Pharmacokinetics
language:en
Short-container-title:Clin Pharmacokinet

Author:

Dockens Randy,Wang Jun-Sheng,Castaneda Lorna,Sverdlov Oleksandr,Huang Shu-Pang,Slemmon Randy,Gu Huidong,Wong Oi,Li Hewei,Berman Robert M.,Smith Christina,Albright Charles F.,Tong Gary

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

http://link.springer.com/content/pdf/10.1007/s40262-012-0005-x.pdf

Reference27 articles.

1. Alzheimer’s Association. Alzheimer’s disease facts and figures. Alzheimers Dement. 2010;6(2):158–94.

2. Gandy S. The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease. J Clin Invest. 2005;115:1121–9.

3. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science. 2002;297:353–6.

4. Hardy J. The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal. J Neurochem. 2009;110:1129–34.

5. Walsh DM, Selkoe DJ. A beta oligomers: a decade of discovery. J Neurochem. 2007;101:1172–84.

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