Clinical Pharmacokinetic, Pharmacodynamic and Drug-Interaction Profile of the Integrase Inhibitor Dolutegravir

Author:

Cottrell Mackenzie L.,Hadzic Tanja,Kashuba Angela D. M.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference57 articles.

1. Adams JL, Greener BN, Kashuba AD. Pharmacology of HIV integrase inhibitors. Curr Opin HIV AIDS. 2012;7(5):390–400.

2. Dejesus E, Cohen C, Elion R, et al. First report of raltegravir (RAL, MK-0518) use after virologic rebound on elvitegravir (EVT, GS 9137) (abstract no. TUPEB032 plus poster). In: 4th IAS Conference on HIV Pathogenesis, Treatment and Prevention, 22–25 Jul 2007, Sydney.

3. Hazuda DJ, Miller MD, Nguyen BY, et al. Resistance to the HIV-integrase inhibitor raltegravir: analysis of protocol 005, a phase 2 study in patients with triple-class resistant HIV-1 infection (abstract no. 8). In: 16th International HIV Drug Resistance Workshop, 12–16 Jun 2007, Barbados.

4. McColl DJ, Fransen S, Gupta S, et al. Resistance and cross-resistance to first generation integrase inhibitors: insights from a phase 2 study of elvitegravir (GS-9137) (abstract no. 9). In: 16th International HIV Drug Resistance Workshop, 12–16 Jun 2007, Barbados.

5. Garrido C, Villacian J, Zahonero N, et al. Broad phenotypic cross-resistance to elvitegravir in HIV-infected patients failing on raltegravir-containing regimens. Antimicrob Agents Chemother. 2012;56(6):2873–8.

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