Phase I study of mitonafide with a 3-day administration schedule: Early interruption due to severe central nervous system toxicity-Reference-Cited by-同舟云学术

Phase I study of mitonafide with a 3-day administration schedule: Early interruption due to severe central nervous system toxicity

Published:1994 Issue:4 Volume:12 Page:277-281
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

D�az-Rubio Eduardo,Mart�n Miguel,L�pez-Vega Jos� Manuel,Casado Antonio,Benavides Ana

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/BF00873041.pdf

Reference10 articles.

1. Braña MF, Castellano JM, Roldán CM: Synthesis and mode(s) of action of a new series of imide derivatives of 3-nitro-1,8-naphthalic acid. Cancer Chemother Pharmacol 4:61?66, 1980

2. Waring MJ, González A, Jiménez A, Vázquez D: Intercalative binding to DNA of antitumor drugs derived from 3-nitro-1,8-naphthalic acid. Nucleic Acid Res 7:217?230, 1979

3. Sinhna BK, Strong J: Mechanism of DNA strand breaks by mitonafide, an imide derivative of 3-nitro-1,8-naphthalic acid. Biochem Pharmacol 34:3845?3852, 1985

4. Hsiang Y, Jiang JB, Liu LF: Topoisomerase II-mediated DNA cleavage by amonafide and its structural analogs. Molecular Pharmacol 36:371?376, 1989

5. Fernández Braña M, Martínez Sanz A, Castellano JM, Martínez Roldán C, Roldán C: Synthesis and cytostatic activity of benz(de)isoquinolin-1,3-diones. Structure-activity relationships. Eur J Med Chem 16:207?212, 1981

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