The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease-Reference-Cited by-同舟云学术

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The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease

Published:2013-05-01 Issue:6 Volume:91 Page:705-713
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Amaral Marta,Outeiro Tiago F.,Scrutton Nigel S.,Giorgini Flaviano

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00109-013-1046-9.pdf

Reference96 articles.

1. Thevandavakkam MA, Schwarcz R, Muchowski PJ, Giorgini F (2010) Targeting kynurenine 3-monooxygenase (KMO): implications for therapy in Huntington’s disease. CNS Neurol Disord Drug Targets 9(6):791–800

2. Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, Prendergast GC (2007) Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res 67(15):7082–7087

3. Han Q, Cai T, Tagle D, Li J (2010) Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. Cellular and molecular life sciences : CMLS 67(3):353–368

4. Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ (2012) Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci 13(7):465–477

5. Ying W (2008) NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid Redox Signal 10(2):179–206

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