The (pro)renin receptors

Author:

Nguyen Geneviève,Contrepas Aurélie

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Drug Discovery,Molecular Medicine

Reference25 articles.

1. Nguyen G, Delarue F, Burcklé C, Bouzhir L, Giller T, Sraer JD (2002) Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109:1417–1427

2. Saris JJ, Derkx FH, De Bruin RJ, Dekkers DH, Lamers JM, Saxena PR, Schalekamp MA, Jan Danser AH (2001) High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin. Am J Physiol 280:H1706–H1715

3. Zhang J, Noble NA, Border WA, Huang Y (2007) Prorenin increases PAI1 expression in vascular smooth-muscle cells (VSMCs); effects that are renin/prorenin receptor-mediated, are markedly potentiated by angiotensinogen and are both AngII-independent and Ang II dependent. J Am Soc Nephrol 18:F–PO297 Abstract

4. Nabi AH, Kageshima A, Uddin MN, Nakagawa T, Park EY, Suzuki F (2006) Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 18(3):483–488

5. Batenburg WW, Krop M, Garrelds I, de Vries R, de Bruin RJA, Burckle C, Muller DN, Bader M, Nguyen G, Danser AH (2007) Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens 25:2441–2453

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