The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity-Reference-Cited by-同舟云学术

The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity

Published:2020-04-18 Issue:6 Volume:94 Page:2149-2162
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

González Eduardo A.,Rindy Alexa C.,Guignet Michelle A.,Calsbeek Jonas J.,Bruun Donald A.,Dhir Ashish,Andrew Peter,Saito Naomi,Rowland Douglas J.,Harvey Danielle J.,Rogawski Michael A.,Lein Pamela J.^ORCID

Funder

National Institute of Neurological Disorders and Stroke

National Institute of General Medical Sciences

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00204-020-02747-w.pdf

Reference45 articles.

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3. Bruun DA, Guignet M, Harvey DJ, Lein PJ (2019) Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication. Neurotoxicology 73:81–84. https://doi.org/10.1016/j.neuro.2019.03.001

4. Chen Y (2012) Organophosphate-induced brain damage: mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies. Neurotoxicology 33:391–400. https://doi.org/10.1016/j.neuro.2012.03.011

5. Copping NA, Adhikari A, Petkova SP, Silverman JL (2019) Genetic backgrounds have unique seizure response profiles and behavioral outcomes following convulsant administration. Epilepsy Behav 101:106547. https://doi.org/10.1016/j.yebeh.2019.106547

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