Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose–response curves for developmental toxicity of phenol in rat and human

Author:

Strikwold Marije,Spenkelink Bert,Woutersen Ruud A.,Rietjens Ivonne M. C. M.,Punt Ans

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference64 articles.

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2. Argus (1997) Oral (gavage) developmental toxicity study of phenol in rats. Protocol number: 916-011. Horsham, Pennsylvania

3. ATSDR (2008) Toxicological profile for phenol. U.S. Department of health and human services, public health service, agency for toxic substances and disease registry (ATSDR), Atlanta (GA)

4. Baars AJ, Theelen RMC, Janssen PJCM, Hesse JM, van Apeldoorn ME, Meijerink MCM, Verdam L, Zeilmaker MJ (2001) Re-evaluation of human-toxicological maximum permissible risk levels. Report no. 711701025. National Institute for Public Health and the Environment (RIVM), Bilthoven

5. Barter ZE, Bayliss MK, Beaune PH, Boobis AR, Carlile DJ, Edwards RJ, Houston JB, Lake BG, Lipscomb JC, Pelkonen OR, Tucker GT, Rostami-Hodjegan A (2007) Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver. Curr Drug Metab 8:33–45

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