Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3
Author:
Funder
Robert Bosch Stiftung
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00204-019-02495-6.pdf
Reference54 articles.
1. Anderson LE, Dring AM, Hamel LD, Stoner MA (2011) Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR). Toxicol Lett 202:148–154. https://doi.org/10.1016/j.toxlet.2011.02.004
2. Arnold KA, Eichelbaum M, Burk O (2004) Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor. Nucl Recept 2:1. https://doi.org/10.1186/1478-1336-2-1
3. Arshad U, Taubert M, Kurlbaum M et al (2018) Enzyme autoinduction by mitotane supported by pharmacokinetic modeling in a large cohort of adrenocortical carcinoma patients. Eur J Endocrinol 179:287–297. https://doi.org/10.1530/EJE-18-0342
4. Auerbach SS, Ramsden R, Stoner MA et al (2003) Alternatively spliced isoforms of the human constitutive androstane receptor. Nucleic Acids Res 31:3194–3207. https://doi.org/10.1093/nar/gkg419
5. Auerbach SS, Stoner MA, Su S, Omiecinski CJ (2005) Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3). Mol Pharmacol 68:1239–1253. https://doi.org/10.1124/mol.105.013417
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol;Environmental Science & Technology;2024-04-09
2. Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure;Journal of Medicinal Chemistry;2023-02-09
3. Searching for Constitutive Androstane Receptor Modulators;Drug Metabolism and Disposition;2022-02-19
4. Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain;Cells;2020-11-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3