A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice
Author:
Funder
JSPS Grants-in-Aid for Scientific Research
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00204-019-02440-7.pdf
Reference40 articles.
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2. Eckel RH et al (2014) 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk. Circulation 129(25 Suppl 2):S76–S99
3. Gan LT, Van Rooyen DM, Koina ME, McCuskey RS, Teoh NC, Farrell GC (2014) Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent. J Hepatol 61:1376–1384
4. Hu X, Tanaka N, Guo R et al (2017) PPARα protects against trans-fatty-acid-containing diet-induced steatohepatitis. J Nutr Biochem 39:77–85
5. Ioannou GN, Morrow OB, Connole ML, Lee SP (2009) Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population. Hepatology 50:175–184
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