Reducing chemotherapy use in clinically high-risk, genomically low-risk pN0 and pN1 early breast cancer patients: five-year data from the prospective, randomised phase 3 West German Study Group (WSG) PlanB trial

Author:

Nitz Ulrike,Gluz OlegORCID,Christgen Matthias,Kates Ronald E.,Clemens Michael,Malter Wolfram,Nuding Benno,Aktas Bahriye,Kuemmel Sherko,Reimer Toralf,Stefek Andrea,Lorenz-Salehi Fatemeh,Krabisch Petra,Just Marianne,Augustin Doris,Liedtke Cornelia,Chao Calvin,Shak Steven,Wuerstlein Rachel,Kreipe Hans H.,Harbeck Nadia

Funder

Genomic Health

Sanofi

Amgen

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference31 articles.

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3. Cheang MC, Chia SK, Voduc D, Gao D, Leung S, Snider J, Watson M, Davies S, Bernard PS, Parker JS, Perou CM, Ellis MJ, Nielsen TO (2009) Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst 101(10):736–750. doi:https://doi.org/10.1093/jnci/djp082

4. Prat A, Cheang MC, Martin M, Parker JS, Carrasco E, Caballero R, Tyldesley S, Gelmon K, Bernard PS, Nielsen TO, Perou CM (2013) Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer. J Clin Oncol 31(2):203–209. doi:https://doi.org/10.1200/JCO.2012.43.4134

5. Gluz O, Liedtke C, Huober J, Peyro-Saint-Paul H, Kates RE, Kreipe HH, Hartmann A, Pelz E, Erber R, Mohrmann S, Mobus V, Augustin D, Hoffmann G, Thomssen C, Janicke F, Kiechle M, Wallwiener D, Kuhn W, Nitz U, Harbeck N, Investigators EC-D (2016) Comparison of prognostic and predictive impact of genomic or central grade and immunohistochemical subtypes or IHC4 in HR+/HER2- early breast cancer: WSG-AGO EC-Doc Trial. Ann Oncol 27(6):1035–1040. doi:https://doi.org/10.1093/annonc/mdw070

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