CORRELATION OF NIHSS WITH SHORT TERM COMPLICATIONS OF ACUTE ISCHEMIC CVA PATIENT RECEIVING THROMBOLYSIS

Abstract

Stroke is characterized as a neurological decit attributed to an acute focal injury of the central nervous system (CNS) by a vascular cause, including cerebral infarction, intracerebral haemorrhage (ICH) and subarachnoid hemorrhage. Thrombolysis is associated with its own complication and side effects and also have its own contraindication which should be kept in mind when thrombolysis is planned for the patient. Of all thrombolysis- related complications, intracerebral haemorrhage causes the most signicant morbidity and mortality. A prospective, longitudinal observational study was done, in which 47 consecutive cases of ischemic CVA, were included from march 2020 to October 2021. The demographics, risk factors, biochemical parameters and outcomes (mortality and complications) were assessed, until discharge or in-hospital death. After 24 hours of thrombolysis, 7 patients had NIHSS between 0-4 (1 patient on arrival),19 patient had NIHSS of 5-15 (15 patients on arrival), 6 patients had NIHSS of 16-20 (11 patients on arrival) and 15 patients had NIHSS of 21-42 (20 patients on arrival). Intra cranial bleed was signicantly more among subjects with NIHSS score (after 24 hours) of 21-42 with 4 out of 7 patients in that group followed by 2 patients with NIHSS of 16-20. Deterioration of power was seen in 3 patients with 2patients of NIHSS of 21-42. Seizure occurred in 2 patients with single patient in NIHSS of 16-20 and 21-42 group respectively. NIHSS at admission and 24hrs after admission is clinical score which could be assessed bedside and helps in assessing prognosis for the patients.