STUDY ON ASSOCIATION OF SERUM FERRITIN & SERUM CERULOPLASMIN IN PREGNANCY: A CASE CONTROL STUDY-Reference-Cited by-同舟云学术

STUDY ON ASSOCIATION OF SERUM FERRITIN & SERUM CERULOPLASMIN IN PREGNANCY: A CASE CONTROL STUDY

Published:2022-02-01 Issue: Volume: Page:31-32
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

Sinha Sanchayan¹,Pal Santasmita²,Chowdhury Piali³,Ghosh Chinmoy⁴

Affiliation:

1. Demonstrator, Dept. of Biochemistry, College of Medicine & Sagore Dutta Hospital, Kolkata.

2. Assistant Professor, Dept. of Biochemistry, Medical College, Kolkata.

3. Demonstrator, Dept. of Biochemistry, NRS Medical College, Kolkata.

4. Assistant Professor, Dept. of Biochemistry, NRS Medical College, Kolkata.

Abstract

Objectives – To compare the levels of serum ferritin & serum ceruloplasmin in pregnant & non- pregnant women & to nd out whether any correlation exists between ferritin & ceruloplasmin levels in pregnancy. Methods –Case population comprised of pregnant women coming for routine antenatal visit in OPD, Nil Ratan Sirkar Medical College & Hospital rd in their 3 trimester of pregnancy. Patient of pre-existing iron deciency anaemia, pregnancy induced hypertension, hypothyroidism, diabetes mellitus, hemoglobinopathies like sickle cell anaemia, thalassemia, were excluded from our study. A control group of healthy, non-pregnant subjects was used for comparison. Results – Serum ferritin level was found to be lower in pregnancy than in non-pregnant women. However the decrease was not found to be statistically signicant. Serum ceruloplasmin was found to be higher in pregnant than in non pregnant women & this increase was found to be statistically signicant. Statistically signicant negative correlation was also been found between serum ferritin & serum ceruloplasmin. Conclusion - Our study establishes the fact that there is increase in serum ceruloplasmin concentration in pregnancy & this increase is further accelerated in iron decient state designated by decreased serum ferritin concentration.

Publisher

World Wide Journals

Reference14 articles.

1. Adebisi, O.Y.; Strayhorn, G. Anemia in pregnancy and race in the United States: Blacks at risk. Fam. Med. 2005, 37, 655–662.

2. Xiong, X.; Buekens, P.; Fraser, W.D.; Guo, Z. Anemia during pregnancy in a Chinese population. Int. J. Gynaecol. Obstet. 2003, 83, 159–164.

3. Kozuki, N.; Lee, A.C.; Katz, J.; Child Health Epidemiology Reference Group. Moderate to severe, but not mild, maternal anemia is associated with increased risk of small-for-gestational-age outcomes. J. Nutr. 2012, 142, 358–362.

4. Levy, A.; Fraser, D.; Katz, M.; Mazor, M.; Sheiner, E. Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery. Eur. J. Obstet. Gynecol. Reprod. Biol. 2005, 122, 182–186.

5. Crispin, P.J.; Sethna, F.; Andriolo, K. Red cell and reticulocyte parameters for the detection of iron deficiency in pregnancy. Clin. Lab. 2019, 65.