AN UPDATE ON ORAL MANIFESTATIONS OF SARS COV-2 INFECTION AND SURVIVAL OUTCOME OF PATIENTS WITH MUCORMYCOSIS : A SYSTEMATIC REVIEW AND META-ANALYSIS.

Abstract

The coronavirus disease (COVID-19) outbreak caused by SARS-CoV-2 is a pandemic infectious disease threatening the world that has been emerged by human-to-human transmission through respiratory droplets. However, the Angiotensin converting enzyme 2 (ACE2) receptor is also considered as the main functional receptor through which SARS CoV-2 gains entry into the body. Now-a-days mucormycosis incidence is increased rapidly due to severe effect of COVID-19 on patient's immune response. Mucormycosis is a rare invasive fungal disease often seen in immunocompromised individuals, mainly in patients with diabetic ketoacidosis, and in patients at concomitant use of steroids. As the prevalence of oral manifestations in effected individuals are still unknown, it has become a broad and current interest. Therefore, this paper aims to summarize the updated literature on oral manifestations of patients with COVID-19 and to analyse the survival outcome of patients with mucormycosis during covid crisis.