CLINICOPATHOLOGICAL STUDY OF A CRITICAL EVALUATION ON LIVER FUNCTIONS IN POSTCHOLECYSTECTOMY CASES

Abstract

Introduction: Gallstones [cholelithiasis] are the most common biliary pathology. It is estimated that gallstones affect 10-15% of the population in Western societies. They are asymptomatic in majority of cases (780). In the UK, the prevalence of gallstones at the time of death is estimated to be 17% and may be increasing. Approximately 1-2% of asymptomatic patients will develop symptoms requiring surgery per year, making cholecystectomy one of the most common operations performed by general surgeon. Aims and objectives: To investigate the clinico-pathological analysis of calculous cholecystitis in relation to liver function tests in all preoperative and post operative cases. Patients are required to undergo liver function test prior to and after their line of management in order to facilitate the investigation. Patients with cholelithiasis as the main cause must undergo a cholecystectomy either open or laparoscopic. Comparative evaluations of derangement of hepatic parameters in the preoperative period of patient undergoing different forms of gallbladder operations (conventional or laparoscopic cholecystectomy). Materials and methods: The study was conducted in a series of 60 cases of chronic calculus cholecystitis. Patients were selected from surgical outpatient Department of Darbhanga Medical College and Hospital. Laheriasarai. The tenure of study was from April 2019 to December 2020. Result: The above study also showed 82% increase in ALT level. In our study ALT was increased in 60 % patients (6% within normal range and 54% more than the normal range) at deation and 70% patients (4% within normal range and 66% more than the normal range) on the second postoperative day in LC. In MC and CC it was about 16-32% and 32-40% respectively during the same period. Conclusion: Ultrasonography was the mainstay in conrmatory diagnosis of gall bladder pathologies and the ndings correlated well with clinical ndings in almost all the cases. It not only revealed the evidence of gall stones in gall bladder with signs of acute or chronic cholecystitis but also other changes in the common bile duct, liver, pancreas and so on.