A PROSPECTIVE STUDY OF MATERNALAND FETAL OUTCOME IN PREECLAMPSIAAND ECLAMPSIA

Abstract

Introduction- Pre eclampsia and eclampsia is one of the leading cause of maternal and fetal morbidity and mortality. This study was undertaken to correlate coagulation prole in patients with pre-eclampsia and eclampsia with maternal and fetal outcome. Materials And Methods- A prospective study was conducted on 164 cases and 70 controls over a period of 2 years. The coagulation prole was carried out on the semiautomated TRINITY coagulometer. The haematological parameters were assessed on fully automated 3 part haematological analyser- TRIVITRON Model-CELLENIUM-19. The patients were classied into mild preeclamptic, severe preeclamptic and eclamptic based on the clinical and haematological parameters. Observations- The maternal and the foetal outcomes were studied and correlated with the coagulation prole. All the cases of mild preeclampsia had favourable maternal and fetal outcome. Out of total 102 cases of severe preeclampsia and eclampsia, 78 had normal coagulation prole and 24 had deranged prole. Thus out of 24 patients with deranged coagulation prole, 21 (87.5%) women had adverse maternal outcome and 24 (100%) had unfavourable fetal outcome. Conclusion- Deranged coagulation prole in preeclampsia and eclampsia is signicantly associated with adverse maternal and fetal outcome. Thus suspecting a deranged coagulation status early in the course of the disease will guide us in management before the patient goes into complications.