Affiliation:
1. Departments of Medicine and Microbiology, University of Florida College of Medicine Gainesville, Florida 32601
Abstract
Insulin, a protein of about 5,700 molecular weight, was delivered by aerosol inhalation to three normal volunteers and to four patients with diabetes mellitus. Direct evidence of absorption of insulin across mucosae of the respiratory tract was an increase in plasma IRI. Biologic activity of insulin absorbed by inhalation was shown by hypoglycemia temporally correlated with the increase in plasma IRI. No untoward reactions were observed.
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
171 articles.
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