Magnetic Resonance-Defined Periportal Steatosis Following Intraportal Islet Transplantation-Reference-Cited by-同舟云学术

Magnetic Resonance-Defined Periportal Steatosis Following Intraportal Islet Transplantation

Published:2003-07-01 Issue:7 Volume:52 Page:1591-1594
ISSN:0012-1797
Container-title:Diabetes
language:en
Short-container-title:

Author:

Markmann James F.¹,Rosen Mark²,Siegelman Evan S.²,Soulen Michael C.²,Deng Shaoping¹,Barker Clyde F.¹,Naji Ali¹

Affiliation:

1. Department of Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania

2. Department of Radiology, University of Pennsylvania Health System, Philadelphia, Pennsylvania

Abstract

There is growing interest in more widespread application of isolated islet transplantation for the treatment of type 1 diabetes; however, the sequelae of long-term islet residence within the liver are unknown. We report herein a consequence of intraportal islet transplantation, specifically the development of periportal hepatic steatosis apparently induced by the local secretion of insulin within the liver.

Publisher

American Diabetes Association

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://journals.org/diabetes/diabetes/article-pdf/52/7/1591/648800/db0703001591.pdf

Reference18 articles.

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5. Shapiro AMJ, Lakey JRT, Ryan EA, Korbutt GS, Toth EL, Warnock GL, Kneteman NN, Rajotte RV: Islet transplantation in seven patients with type I diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343:230–238,2000

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