Affiliation:
1. Department of Nutritional Sciences, Faculty of Medicine, Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, University of Toronto Toronto, Ontario, Canada
Abstract
Objectives
To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM).
Research Design and Methods
Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossover design. Both diets were of similar composition (57% carbohydrate, 23% fat, and 34 g/day dietary fiber), but the low-GI diet had a GI of 58 compared with 86 for the high-GI diet.
Results
Small and similar amounts of weight were lost on both diets: 2.5 kg on high-GI diet and 1.8 kg on low-GI diet. On the low-GI diet, the mean level of serum fructosamine, as an index of overall blood glucose control, was lower than on the high-GI diet by 8% (P <0.05), and total serum cholesterol was lower by 7% (P <0.01).
Conclusions
In overweight patients with NIDDM, reducing diet GI improves overall blood glucose and lipid control.
Publisher
American Diabetes Association
Subject
Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
163 articles.
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