The Effect of Cinnamon on A1C Among Adolescents With Type 1 Diabetes-Reference-Cited by-同舟云学术

The Effect of Cinnamon on A1C Among Adolescents With Type 1 Diabetes

Published:2007-04-01 Issue:4 Volume:30 Page:813-816
ISSN:0149-5992
Container-title:Diabetes Care
language:en
Short-container-title:

Author:

Altschuler Justin A.¹,Casella Samuel J.²,MacKenzie Todd A.³,Curtis Kevin M.⁴

Affiliation:

1. Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire

2. Department of Pediatric Endocrinology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

3. Department of General Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

4. Department of Emergency Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Abstract

OBJECTIVE—The purpose of this study was to determine the effect of cinnamon on glycemic control in adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS—Using a prospective, double-blind, placebo-controlled design, 72 adolescent type 1 diabetic subjects were treated in an outpatient setting with cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. A1C, total daily insulin intake, and adverse events were recorded and compared between groups. RESULTS—There were no significant differences in final A1C (8.8 vs. 8.7, P = 0.88), change in A1C (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or number of hypoglycemic episodes between the cinnamon and placebo arms. CONCLUSIONS—Cinnamon is not effective for improving glycemic control in adolescents with type 1 diabetes.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://diabetesjournals.org/care/article-pdf/30/4/813/596352/zdc00407000813.pdf

Reference19 articles.

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2. Jarvill-Taylor KJ, Anderson RA, Graves DJ: A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3–L1 adipocytes. J Am Coll Nutr 20:327–336, 2001

3. Broadhurst CL, Polansky MM, Anderson RA: Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric Food Chem 48:849–852, 2000

4. Imparl-Radosevich J, Deas S, Polansky MM, Baedke DA, Ingebritsen TS, Anderson RA, Graves DJ: Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Horm Res 50:177–182, 1998

5. Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y: Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats. Diabetes Res Clin Pract 62:139–148, 2003

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